Los Angeles Dodgers two-way star Shohei Ohtani left Thursday’s game against the?Pittsburgh Pirates in the top of the seventh inning because of left knee inflammation.

Ohtani ?was 2-for-2 with his ?second home ?run in as many ?games and had reached base four times before his departure. Santiago ?Espinal replaced him as the Dodgers’ designated ?hitter.

After the Dodgers’ 8-6 win over the Pirates, Los Angeles??manager Dave Roberts said his level of concern regarding?Ohtani?is “not high.” It was unclear when the ailment started, as?Ohtani??hadn’t told Roberts of any issues with the knee until the sixth ?inning.

“I think we tried to be smart about it,” Roberts said. “Talked to the trainer who said he ?had a little (soreness) behind ?the knee. ... Just wanted to be smart and not push it.”

As to whether?Ohtani?will ?play the series ?opener against the White Sox in Chicago on ?Friday, Roberts said, “I feel good about him being ?in there tomorrow, ?but obviously with the travel tonight, we’ll just kind of see how he comes in.”

Earlier in the game, the Dodgers also lost ?starting pitcher Justin ?Wrobleski, who took a 96.2 mph (154.8 kph) comebacker off his ?upper leg ?and then collided with ?Bryan Reynolds on the latter’s ?infield ?single in the fifth inning.

The left-hander came out due to a right hamstring contusion. He ?allowed four runs on six hits, including a pair of home runs,?in 4??innings.

Kyle Tucker ripped a two-run single, Miguel Rojas drove in two runs ?and Andy Pages and Dalton Rushing each scored on a wild pitch for the Dodgers.

Los Angeles ?reliever Jack Dreyer (3-1) struck out two batters in one scoreless inning.

The Dodgers won twice in the three-game series.

Ohtani opened the scoring in the ?third? by depositing a ?3-2 sweeper from Mitch Keller over ?the wall in right-center field for a solo shot. The long ball was the 13th of ?the season for Ohtani, who launched a two-run blast in the Dodgers’ 9-8 loss to the Pirates on Wednesday.