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October 27, 2026
 

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TRANSPLANTS

RiHeart, an iPS cell-based sheet, has been put into practical use for heart surgery after it was exhibited at the 2025 Osaka Expo.
JAPAN / FOCUS
Oct 20, 2026
Technologies seen at Osaka Expo increasingly being put into practice
Heart muscle cells, a “human washing machine” and a flying car have all seen new interest or progress since the event.
A lab-grown heart made from induced pluripotent stem cells in Osaka in April 2025
JAPAN / Science & Health
Sep 30, 2026
Heart muscle stem cells see first clinical use in surgery in Japan
Sheets of muscle cells derived from regenerative products known as iPS cells were transplanted into the heart of a patient in her 50s.
Long-term safety has been confirmed after neural progenitor cells derived from iPS cells were transplanted into patients with spinal cord injuries, a team of researchers at Keio University has said.
JAPAN / Science & Health
Jul 21, 2026
Long-term safety of iPS spinal cord therapy confirmed in Japan
The team plans to launch an investigator-initiated clinical trial as early as next year to bring it into practical use.
A Japanese research team plans to conduct clinical research to temporarily transplant a pig's kidney into a human fetus with severe kidney disease, a procedure expected to be the world's first fetal xenotransplantation.
JAPAN / Science & Health
Jul 21, 2026
Japan team eyes world’s first pig-kidney transplant to human fetus
The therapeutic method is supposed to be temporary treatment until dialysis becomes possible for the baby.
Notebooks and related materials seized by the Tokyo Metropolitan Police Department, on Tuesday in Tokyo's Chiyoda Ward
JAPAN / Crime & Legal
Jul 8, 2026
Three arrested in Japan over illegal brokering of overseas organ transplant
It was the first time for Japanese police to take action against suspected organ transplant mediation for fees, according to Tokyo’s Metropolitan Police Department.
Clinical trials are being planned in Japan where modified pig kidneys would be transplanted into humans.
JAPAN / Science & Health
Jun 29, 2026
Two hospitals in Japan to conduct pig-to-human kidney transplant clinical trials in 2028
The startup spun out of Meiji University said it would aim to obtain production and marketing authorization after confirming their safety through the trials.
Researchers are able to use cow tendons in humans without triggering an immune response through a unique “decellularization” technology.
JAPAN / Science & Health
Jun 25, 2026
Cow tendons eyed as ligament material for ACL reconstruction surgery
One of the researchers involved hopes to eventually apply the cow-derived material to the reconstruction of other ligaments in the knee, as well as in the ankle and inner elbow.
Organ transplants are sometimes called off due to staff shortages, for example, at medical institutions in Japan.
JAPAN / Science & Health
May 28, 2026
Health ministry to give financial aid to organ transplant hospitals
The aid program is designed to reduce cases in which transplants are canceled due to staff shortages, as more people become organ donors.
Japan's health ministry has imposed restrictions on blood and organ donations from people who have stayed in Britain or elsewhere in Europe between 1980 and 2004.
JAPAN
Apr 15, 2026
Japan to lift organ donation curbs for those who have stayed in Europe
The change is expected to take effect as early as this autumn.
Until now, heart transplant patients in Japan who have ventricular assist devices and are given Status 1 priority were ranked by waiting time regardless of urgency.
JAPAN / Science & Health
Mar 24, 2026
Patients with urgent, high-risk conditions to get heart transplant priority
The policy shift aims to reduce deaths of patients waiting for transplants, particularly those at high risk of dying from complications.
St. Luke's International Hospital in Tokyo's Chuo Ward
JAPAN / Science & Health
Feb 18, 2026
Two women in Japan give birth after frozen ovarian transplants
It is rare that post-transplant pregnancies and childbirths by those who entered menopause due to cancer treatment have been closely monitored.
A clinical trial by a Tokyo-based venture company has confirmed that transplanting cardiac muscle cell clusters created from iPS cells into patients with severe heart failure improved their cardiac functions and symptoms.
JAPAN / Science & Health
Dec 13, 2025
Tokyo startup confirms efficacy of iPS cell-derived heart muscle transplants
According to Friday’s announcement, the transplant was performed on 10 patients, and no major safety issues were confirmed.
Russian President Vladimir Putin walks with Chinese President Xi Jinping before a military parade in Beijing's Tiananmen Square on Wednesday.
WORLD / Science & Health / EXPLAINER
Sep 5, 2025
Could humans live forever, as Putin was heard telling Xi?
Maybe not, experts say, though serious research is increasingly revealing more about why we age — and how we could try to stop it.
A regenerative medicine startup, Kyoto-based iHeart Japan, said Monday that it has conducted a clinical trial to transplant a treatment sheet containing cardiac muscle cells derived from human induced pluripotent stem cells into a patient with a heart muscle disease.
JAPAN / Science & Health
Jul 29, 2025
Japan startup transplants iPS cells for heart treatment in clinical trial
The layered sheet containing three types of cells and gelatin particles were placed on the surface of the heart, and are expected to improve the heart’s contractions.
It is the first transplant surgery in the hospital's clinical trial for treating Type 1 diabetes through the transplantation of pancreatic cell sheets made from iPS cells.
JAPAN
Apr 15, 2025
Kyoto hospital succeeds in iPS sheet transplant to diabetic patient
It is the first clinical application of such sheets in Japan.
The Jikei University School of Medicine in Tokyo's Minato Ward. A team from the university has successfully transplanted kidneys between rat fetuses.
JAPAN / Science & Health
Apr 11, 2025
Japanese research team succeeds in fetal rat kidney transplant
The success of the team at Jikei University School of Medicine in Tokyo marks a key step toward clinical studies involving cross-species organ transplantation.
Keio University in Tokyo's Minato Ward. The university's ethics committee has approved clinical research that would lead to the first uterine transplant procedure in Japan.
JAPAN / Science & Health
Feb 28, 2025
Keio University ethics panel OKs uterus transplant clinical trial
The university will consider whether to carry out the research, which would be the first uterine transplant procedure in Japan.
The third patient to receive a genetically engineered pig kidney is thriving post-transplant, providing valuable insights into animal-to-human organ replacement and bringing the field closer to clinical trials.?
COMMENTARY / World
Jan 27, 2025
Why a recent pig kidney transplant is a major advance
The 53-year-old woman who received the genetically modified animal organ is the ideal recipient to push science forward.
Currently, if a hospital declines an organ due to logistical or other issues, it is instead offered to a patient at another facility.
JAPAN / Science & Health
Dec 6, 2024
Multi-facility option set for patients awaiting organ transplants
The health ministry aims to address situations in which high-priority patients miss out on transplants due to logistical issues at their hospital.
A pig that is pregnant with piglets suited for cross-species transplants
JAPAN / Science & Health
Nov 25, 2024
Startup transplants pig kidney into monkey for first time in Japan
It is hoped that the operation will provide insights into the future use of animal kidneys in humans.
Two Japanese climbers die on remote Himalayan peak in Nepal
Rescuers have recovered the bodies of two Japanese climbers missing for over a week on a remote Himalayan mountain.
Aging Japanese village turns to Peru in search of new residents
Guests from Peru's Belen district interact with a baby in Nanmoku village in Gunma Prefecture.
Budget-friendly restaurant chain Saizeriya succumbs to rising costs
A Tokyo branch of Saizeriya, a chain of family-style Italian restaurants
U.S. has for years asked Musk to alter Starlink service in Ukraine and Middle East, sources say
A Ukrainian soldier sets up a Starlink satellite internet system near the frontline in the Donetsk region, Ukraine, on Oct. 16
U.S. military bans Chinese-made BYD cars from key air base in Okinawa
An F-22 Raptor lands at Kadena Air Base in Kadena, Okinawa Prefecture on Oct. 9. The base is a crucial hub for U.S. military operations in the region.
A dramatic bear hunt in a midsize Japanese city could be a harbinger of what is to come
Zookeeper Tetsuo Iso at the site of frantic search for a wild bear in Utsunomiya on June 9. Iso, 65, was asked by the prefectural government to help capture the bear and it was his shot with a tranquilizer gun that put an end to the saga.
How this long-term resident avoids the annoying tourist label in Japan
Tourists enjoy themselves while crossing the famous Shibuya Crossing in Tokyo on Oct. 12.
What can Asia do to avoid crossing crucial climate tipping points?
Motorists drive through a road covered with smog from wildfires nearby in Ogan Ilir in Indonesia's South Sumatra province on Sept. 25.
Baku championships showcase rising standards in global sumo
Ryan Roddy (second from left back) is pictured with the Ireland sumo team at this month's World Sumo Championships in Baku, Azerbaijan.
91AV原创 permanent residency reform has a glaring blind spot
Japan's immigration reforms risk creating uncertainty by tying permanent residency more closely to language proficiency before clear assessment standards and supporting infrastructure are in place.

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